one-pot green synthesis of isoxazol-5(4h)-one derivatives by dowex1-x8oh in water
;Setamdideh Davood
meditsinskaia radiologiia2016Vol. 81pp. 971-978
199
davood2016journalone-pot
Abstract
4-arylmethylidene-3-methylisoxazol-5(4H)-ones and
4-arylmethyl-idene-3-phenylisoxazol-5(4H)-ones have been synthesized in the
one-pot three-component synthesis in the presence of Dowex1-x8OH as catalyst
in water. The products have been obtained in high yields (90-95%) and proper
reaction times (1-5 hours). This method has eco-friendly profile and
operational simplicity.