This study aims to examine the relationship between variables in the model that explains the intention to use an application based android. This study confirms several variables which in previous studies are still a debate, namely the influence of knowledge on the intention to use. This study also uses attitudes to mediate the influence of website quality and electronic Word of Mouth (e-WOM), with the consideration that the discussion of the direct influence on adoption behavior will ignore the cognitive aspects of consumers in making purchasing decisions. This research is a survey research with a questionnaire. The populations in this study are all online shopping consumers who have adopted an application based android in the Special Region of Yogyakarta. The number of respondents in this study was 206 consumers. Data analysis in this study used structural equation modeling (SEM). The results showed that knowledge has a positive effect on perceived relative advantage. Web quality and e-WOM affect attitudes, and relative advantages and attitudes influence the intention to use. The results of the study show that the intention to use model is acceptable. All proposed hypotheses are also supported. Knowledge has a positive effect on relative advantages. Website quality, e-WOM and relative advantages have an influence on attitudes, and attitudes influence the intention to use the android application.