We described two cases of infantile hepatic hemangioendothelioma: one with a solitary lesion and the other with multicentric lesions. Clinical presentation was with no liver symptoms in case 1, and hepatomegaly, failure to thrive, and palpable abdominal mass in case 2. Diagnostic imaging revealed single tumor formation in case 1 and multiple nodules in the liver in case 2. Dilemmas related to nature of the tumor were solved by microscopic analysis. The patient with the clinical appearance of a single lesion was successfully operated. The patient with multiple lesions in the liver tissue showed complete involution after corticotherapy.