Premenstrual syndrome is defined as a combination of physical and mental symptoms that have a significant impact on a woman’s quality of life and develop into the second phase of the menstrual cycle. Many patients have not been diagnosed, and therefore pathogenetic treatment is not carried out, although these complaints may disrupt the daily lives of patients and relationships with others. The article presents a review of the literature and studies that assessed the effectiveness of various treatment options (antidepressants, hormone therapy, lifestyle modification and herbal therapy).