Asymmetry syndrome is one of the forms of delay of neuromotor development, which appears in newborns and infants, and belongs to the group of risk babies (present prenatal, perinatal or postnatal risk factors).Asymmetry syndrome can be manifested with asymmetric head position, trunk asymmetry, and upper and lower extremity asymmetry on the same side.Our study included 64 babies with the asymmetry syndrome who were treated at our Clinic. The most frequent risk factors were intracranial hemorrhages, hypoxicischemic encephalopathy and asphyxia. Clinical expression of asymmetry was correlated with ultrasound of CNS. The most frequent finding was a complete asymmetry of the head, trunk and extremities.