The bluefin tuna fishery in the Mediterranean has a long history of human interaction. In recent times, this fishery has become the central source of bluefin tuna for core nations, particularly Japan. This process was set off in large part by the growth of global fish markets, driven by the valuable sushi and sashimi market, and overfishing of other bluefin stocks in other parts of the world. The transformation of this fishery from an artisanal trap fishery to a globalized industrial fishery has had a number of social and environmental consequences. Based on in-depth fieldwork and historical research, this paper examines the political economy of the bluefin tuna fishery in the Mediterranean, with a focus on Sicily. It provides a descriptive history of the changing conditions in this fishery, paying special attention to the modern fishery. This research contributes to the discussions regarding the globalization and industrialization of agri-foodsystems and environmental degradation.