a new cytotoxic 19-nor-cardenolide from the latex of antiaris toxicaria
;Wen-Li Mei;Zhen-Chang Wen;Yu-Juan Gan;Jiao Wu;Dong-Mei Que;Hao-Fu Dai
Journal of ethnopharmacology2009Vol. 14pp. 3694-3699
85
mei2009moleculesa
Abstract
A new nor-cardenolide, named toxicarioside H (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Its structure was elucidated on the basis of HRFAB-MS and spectroscopic techniques (IR, UV, 1D and 2D NMR). Compound 1 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by MTT method.