Due to earthquake science advances, the prediction of probable earthquake intensity in different regions is approximately possible. But it is not possible to predict the time of earthquake occurrence, so there should be considered some other measures to have the lowest losses during this natural event. This research aims to predict the losses and damages caused by the earthquake and to utilize statistics and population structure using SELENA software. HAZARD US method is used in this study. In this method, the response curve achieved based on soil type and IBC-2006 standard and damping effect of structures listed on the FEMA 440 approach is applied. The results show that because of old structures and population density, the fabric of the old city including regions 1 to 4 and 10 to 12are more vulnerable.