No abstract available. Article truncated at 150 words. Evins AE, Cather C, Pratt SA, et al. Maintenance treatment with varenicline for smoking cessation in patients with schizophrenia and bipolar disorder: a randomized clinical trial. JAMA. 2014;311(2):145-54. It is estimated that > 50% of people with mental illness smoke cigarettes. Pharmacotherapy with varenicline has been shown to reach an abstinence rate of 24% at 12 weeks when compared to placebo at 5%. Once off pharmacotherapy, the maintenance of smoking cessation decreases to 12% at 6 months. This study examined whether a prolonged maintenance course of varenicline over 40 weeks is associated with increased rates of smoking cessation. The study was a randomized double blind placebo-controlled trial done in 10 community centers. 203 patients met inclusion criteria and entered a 12 week smoking cessation program with varenicline and cognitive behavioral therapy (CBT). 87 patients completed the initial smoking cessation to continue onto the maintenance phase. Patients were randomized to receive ...