Signals from Global Navigational Satellite Systems (GNSS) when integrated with surface meteorological parameters can be used to sense atmospheric water vapour. Using gLAB software and employing precise point positioning techniques, zenith troposphere delays (ZTD) for a GPS base station at KNUST, Kumasi have been computed and used to retrieve Precipitable Water (PW). The PW values obtained were compared with products from ERA-Interim and NCEP reanalysis data. The correlation coefficients, r, determined from these comparisons were 0.839 and 0.729 for ERA-interim and NCEP respectively. This study has demonstrated that water vapour can be retrieved with high precision from GNSS signal. Furthermore, a location map have been produced to serve as a guide in adopting and installing GNSS base stations in Ghana to achieve a country wide coverage of GNSS based water vapour monitoring.