Pd-catalyzed oxidative CH/CH direct coupling of heterocyclic N-oxides.

Pd-catalyzed oxidative CH/CH direct coupling of heterocyclic N-oxides.

Liu, Wei;Li, Yahui;Wang, Yue;Kuang, Chunxiang;
Organic letters 2013 Vol. 15 pp. 4682-5
274
liu2013pdcatalyzedorganic

Abstract

A highly efficient protocol for C-H/C-H cross-coupling has been found to occur between 2-aryl-1,2,3-triazole N-oxides and pyridine N-oxide derivatives. In addition, two homocoupling reactions of 2-substituted 1,2,3-triazole N-oxides and some pyridine N-oxide derivatives were developed. A possible pathway of C-H/C-H direct coupling is discussed.

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12158
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10.1021/ol4019776
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