Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
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Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

Campbell JD;Yau C;Bowlby R;Liu Y;Brennan K;Fan H;Taylor AM;Wang C;Walter V;Akbani R;Byers LA;Creighton CJ;Coarfa C;Shih J;Cherniack AD;Gevaert O;Prunello M;Shen H;Anur P;Chen J;Cheng H;Hayes DN;Bullman S;Pedamallu CS;Ojesina AI;Sadeghi S;Mungall KL;Robertson AG;Benz C;Schultz A;Kanchi RS;Gay CM;Hegde A;Diao L;Wang J;Ma W;Sumazin P;Chiu HS;Chen TW;Gunaratne P;Donehower L;Rader JS;Zuna R;Al-Ahmadie H;Lazar AJ;Flores ER;Tsai KY;Zhou JH;Rustgi AK;Drill E;Shen R;Wong CK; ;Stuart JM;Laird PW;Hoadley KA;Weinstein JN;Peto M;Pickering CR;Chen Z;Van Waes C;;
Cell reports 2018 Vol. 23 pp. -
442
jd2018cellgenomic,

Abstract

This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smoking and/or human papillomavirus (HPV). SCCs harbor 3q, 5p, and other recurrent chromosomal copy-number alterations (C …

Keywords

Tumor National Center for Biotechnology Information NCBI NLM MEDLINE genetic gene expression regulation humans pubmed abstract nih national institutes of health national library of medicine research support N.I.H. Extramural cell line neoplastic* Polymorphism carcinoma dna methylation intramural genomics / methods pmid:29617660 pmc6002769 doi:10.1016/j.celrep.2018.03.063 joshua d campbell christina yau carter van waes squamous cell / classification* squamous cell / genetics squamous cell / immunology squamous cell / metabolism epithelial-mesenchymal transition metabolic networks and pathways*

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