Zebrafish hox clusters and vertebrate genome evolution
Abstract
HOX genes specify cell fate in the anterior-posterior axis of animal embryos. Invertebrate chordates have one HOX cluster, but mammals have four, suggesting that cluster duplication facilitated the evolution of vertebrate body plans. This report shows that zebrafish have seven hox clusters. Phylogen …
Keywords
Evolution
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
animals
pubmed abstract
nih
national institutes of health
national library of medicine
models
research support
non-u.s. gov't
u.s. gov't
non-p.h.s.
P.H.S.
Molecular*
Genes
Phylogeny
chromosome mapping
zebrafish / genetics*
genome*
multigene family*
gene duplication
homeobox*
pmid:9831563
doi:10.1126/science.282.5394.1711
a amores
a force
j h postlethwait
chromosomes / genetics
pseudogenes
Citation
ID:
121215
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