Prospective study to determine clinical relevance of detection of pneumococcal DNA in sera of children by PCR
Abstract
We undertook a prospective study to evaluate the accuracy of PCR of serum (aimed at the pneumococcal pneumolysin gene) at detecting pneumococcal infections in infants and children. The assay was positive for all blood and cerebrospinal fluid culture-positive samples and for 38 and 44% of patients wi …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
adult
age factors
adolescent
middle aged
Child
Infant
Prospective Studies
preschool
DNA
sensitivity and specificity
pneumonia
pneumococcal / diagnosis*
evaluation studies as topic
meningitis
pneumococcal / microbiology
streptococcus pneumoniae / genetics
streptococcus pneumoniae / isolation & purification*
bacteremia / microbiology
pneumococcal infections / diagnosis*
bacterial / blood*
r dagan
bacterial / genetics
pneumococcal infections / microbiology
bacterial proteins
streptolysins / genetics
nasopharynx / microbiology
polymerase chain reaction*
carrier state / microbiology
bacteremia / diagnosis
pmid:9508293
pmc104606
doi:10.1128/jcm.36.3.669-673.1998
o shriker
r levy
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Citation
ID:
120865
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