Analyses of health outcomes from the 5 sites participating in the Africa and Asia clinical efficacy trials of the oral pentavalent rotavirus vaccine
Abstract
Combining data from the 5 sites strengthens the precision of VE estimates and reveals rising VE with increased RVGE severity. Extrapolating data from VE against severe GE and RVGE suggest that 39% of severe GE episodes during the first year of life were due to rotavirus, highlighting substantial, po …
Keywords
Administration
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
Infant
Clinical Trial
Phase III
Randomized Controlled Trial
Double-Blind Method
Multicenter Study
Genotype
severity of illness index
rotavirus infections / epidemiology
rotavirus infections / prevention & control*
rotavirus vaccines / immunology*
vaccines
attenuated / administration & dosage
attenuated / immunology
gastroenteritis / epidemiology
gastroenteritis / prevention & control*
rotavirus vaccines / administration & dosage*
feces / virology
rotavirus / isolation & purification
developing countries
oral
asia / epidemiology
placebos / administration & dosage
vaccination / methods*
rotavirus / classification
rotavirus / genetics
k zaman
africa / epidemiology
kathleen m neuzil
pmid:22520132
doi:10.1016/j.vaccine.2011.08.124
robert f breiman
gastroenteritis / pathology
rotavirus infections / pathology
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120227
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