Dissociation in Pharmacokinetic Attenuation Between Central Dopamine D2 Receptor Occupancy and Peripheral Blood Concentration of Antipsychotics: A Systematic Review

Dissociation in Pharmacokinetic Attenuation Between Central Dopamine D2 Receptor Occupancy and Peripheral Blood Concentration of Antipsychotics: A Systematic Review

Shin Kurose;Yu Mimura;Hiroyuki Uchida;Keisuke Takahata;Euitae Kim;Takefumi Suzuki;Masaru Mimura;Hiroyoshi Takeuchi;
the journal of clinical psychiatry 2020 Vol. 81 pp. 0-0
240
kurose2020thedissociation

Abstract

Pharmacokinetics of antipsychotics are generally slower centrally than peripherally. This review examined the possible dissociation between central D2 receptor occupancy with antipsychotics and their peripheral blood concentrations.

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