Human and murine cytotoxic T cells specific to respiratory syncytial virus recognize the viral nucleoprotein (N), but not the major glycoprotein (G), expressed by vaccinia virus recombinants
Abstract
The viral antigens recognized by cytotoxic T cells (CTL) have not been defined in most viruses infecting mouse or man. Natural or artificial virus recombinants can be used to determine the antigen specificity of CTL directed against viruses with segmented genomes, such as influenza, but this techniq …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
Viral Proteins / genetics
respiratory syncytial viruses / immunology*
glycoproteins / immunology*
t-lymphocytes
cytotoxic / immunology*
p j openshaw
viral proteins / immunology*
vaccinia virus / immunology
c r bangham
b a askonas
pmid:2431051
capsid / immunology*
epitopes / immunology
glycoproteins / genetics
hla antigens / immunology
recombinant proteins / genetics
recombinant proteins / immunology
viral core proteins / immunology*
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119087
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