Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?
Abbott DH;Barnett DK;Bruns CM;Dumesic DA;;
human reproduction update1970Vol. 11pp. -
288
dh1970humanandrogen
Abstract
The aetiology of polycystic ovary syndrome (PCOS) remains unknown. This familial syndrome is prevalent among reproductive-aged women and its inheritance indicates a dominant regulatory gene with incomplete penetrance. However, promising candidate genes have proven unreliable as markers for the PCOS …