Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?

Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?

Abbott DH;Barnett DK;Bruns CM;Dumesic DA;;
human reproduction update 1970 Vol. 11 pp. -
288
dh1970humanandrogen

Abstract

The aetiology of polycystic ovary syndrome (PCOS) remains unknown. This familial syndrome is prevalent among reproductive-aged women and its inheritance indicates a dominant regulatory gene with incomplete penetrance. However, promising candidate genes have proven unreliable as markers for the PCOS …

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