Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice.
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Recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fab is effective therapeutically when introduced directly into the lungs of RSV-infected mice.

J E Crowe, Jr, B R Murphy, R M Chanock, R A Williamson, C F Barbas, 3rd, D R Burton;J E Crowe, Jr;B R Murphy;R M Chanock;R A Williamson;C F Barbas, 3rd;D R Burton;
Proceedings of the National Academy of Sciences of the United States of America 1994 Vol. 91 pp. 1386-
185
burton1994proceedingsrecombinant

Abstract

Previously, recombinant human respiratory syncytial virus (RSV) monoclonal antibody Fabs were generated by antigen selection from random combinatorial libraries displayed at the tip of filamentous phage. Two such Fabs, which exhibited high binding affinity ...

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DOI:
10.1073/pnas.91.4.1386
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC43163/

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ID: 118734
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