Regulation of androgen-responsive transcription by the chromatin remodeling factor CHD8

Regulation of androgen-responsive transcription by the chromatin remodeling factor CHD8

Menon T;Yates JA;Bochar DA;;
molecular endocrinology (baltimore, md) 2010 Vol. 24 pp. -
313
t2010molecularregulation

Abstract

The androgen receptor (AR) mediates the effect of androgens through its transcriptional function during both normal prostate development and in the emergence and progression of prostate cancer. AR is known to assemble coactivator complexes at target promoters to facilitate transcriptional activation …

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