In vitro and in vivo inhibition of ortho- and paramyxovirus infections by a new class of sulfonic acid polymers interacting with virus-cell binding and/or fusion.
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In vitro and in vivo inhibition of ortho- and paramyxovirus infections by a new class of sulfonic acid polymers interacting with virus-cell binding and/or fusion.

S Ikeda, J Neyts, S Verma, A Wickramasinghe, P Mohan, E De Clercq;S Ikeda;J Neyts;S Verma;A Wickramasinghe;P Mohan;E De Clercq;
Antimicrobial agents and chemotherapy 1994 Vol. 38 pp. 256-
127
clercq1994antimicrobialin

Abstract

A series of sulfonic acid polymers were shown to be potent and selective inhibitors of respiratory syncytial virus (RSV) and influenza A virus. The compounds inhibit the replication of RSV and influenza A virus in HeLa and MDCK cells, at concentrations ...

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DOI:
10.1128/aac.38.2.256
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC284437...

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ID: 118073
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