Nonhuman primate models of polycystic ovary syndrome
Abstract
With close genomic and phenotypic similarity to humans, nonhuman primate models provide comprehensive epigenetic mimics of polycystic ovary syndrome (PCOS), suggesting early life targeting for prevention. Fetal exposure to testosterone (T), of all nonhuman primate emulations, provides the closest PC …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
pregnancy
research support
non-u.s. gov't
female
N.I.H.
Extramural
Disease Models
david h abbott
daniel a dumesic
age factors
animal*
newborn
phenotype
Polycystic Ovary Syndrome / metabolism*
polycystic ovary syndrome / embryology
pmid:23370180
pmc3683573
doi:10.1016/j.mce.2013.01.013
lindsey e nicol
insulin resistance
primates
testosterone / physiology
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117828
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