CD4+ T cells clear virus but augment disease in mice infected with respiratory syncytial virus. Comparison with the effects of CD8+ T cells.
W H Alwan, F M Record, P J Openshaw;W H Alwan;F M Record;P J Openshaw;
clinical and experimental immunology1992Vol. 88pp. 527-
259
openshaw1992clinicalcd4+
Abstract
Respiratory syncytial (RS) virus-specific T cell lines were derived from the spleens of BALB/c mice primed by intranasal infection with RS virus. The lines were expanded by repeated antigenic stimulation in vitro, and separated into CD4+ and CD8+ T cell-enriched ...