In vitro antiviral activities of sulfated polysaccharides from a marine microalga (Cochlodinium polykrikoides) against human immunodeficiency virus and other enveloped viruses
Abstract
A marine microalga, Cochlodinium polykrikoides, produces extracellular sulfated polysaccharides. Isolation and purification of the polysaccharides were accomplished by precipitation with ethanol and Cetavlon, followed by DEAE-cellulose column chromatography (polysaccharides A1 and A2). These polysac …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Cultured
chromatography / methods
kidney / virology
spectrophotometry
drug evaluation
antiviral agents / pharmacology*
simplexvirus / drug effects
cell division / drug effects
respiratory syncytial viruses / drug effects
tumor cells
cell line / virology
virus replication / drug effects
pmid:8580094
doi:10.1016/0141-8130(95)98157-t
m hasui
m matsuda
s shigeta
antiviral agents / isolation & purification
cell line / drug effects
preclinical
eukaryota / chemistry*
hiv-1 / drug effects*
influenza a virus / drug effects
kidney / cytology
laryngeal neoplasms / pathology
polysaccharides / chemistry
polysaccharides / isolation & purification*
polysaccharides / pharmacology*
infrared
sulfates
Access
Citation
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117306
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