Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection
Abstract
The goal of this study was to examine the changes in lymphocyte populations in rectal mucosa during HIV infection and to study their relationship to mucosal immunity and to systemic depletion of CD4 lymphocytes. Rectal biopsies from 58 HIV-infected subjects and eight controls were studied. Frozen re …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
non-p.h.s.
female
male
P.H.S.
d p kotler
cd4-cd8 ratio
hiv infections / pathology*
lymphocyte count
pmid:9030865
pmc1904578
doi:10.1111/j.1365-2249.1997.236-ce1111.x
f clayton
g snow
acquired immunodeficiency syndrome / pathology
cd4-positive t-lymphocytes / cytology*
intestinal mucosa / cytology*
macrophages / cytology
rectum / cytology*
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117216
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