Forming functional fat: a growing understanding of adipocyte differentiation
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Forming functional fat: a growing understanding of adipocyte differentiation

Ana G. Cristancho;Mitchell A. Lazar;Ana G. Cristancho;Mitchell A. Lazar;
nature reviews molecular cell biology 2011 Vol. 12 pp. 722-734
240
cristancho2011natureforming

Abstract

The differentiation of adipocytes from mesenchymal stem cells, known as adipogenesis, occurs in two stages, commitment and terminal differentiation, both of which are tightly regulated by mechanical and molecular cues. A better understanding of the underlying mechanisms may identify therapeutic targets for metabolic diseases.

Keywords

gene expression development metabolism metabolic diseases epigenomics cell signalling fats

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DOI:
doi:10.1038/nrm3198
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http://dx.doi.org/10.1038/nrm3198

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