Keeping CRISPR/Cas on-Target
Abstract
CRISPR/Cas, a microbial adaptive immune system, has recently been reshaped as a versatile genome editing approach, endowing genome engineering with high efficiency and robustness. The DNA endonuclease Cas, a component of CRISPR system, is directed to specific target within genomes by guide RNA (gRNA …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
reproducibility of results
research support
non-u.s. gov't
genetic engineering
faheem ahmed khan
crispr-cas systems*
muhammad jamal
epigenesis
pmid:26453843
gang cao
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116913
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