Familial and acquired hemophagocytic lymphohistiocytosis
Abstract
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of severe hyperinflammation caused by the uncontrolled proliferation of activated lymphocytes and histiocytes secreting high amounts of inflammatory cytokines. Cardinal signs and symptoms are prolonged fever, hepatosplenomegaly …
Keywords
immunity
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
diagnosis
humans
pubmed abstract
nih
national institutes of health
national library of medicine
risk factors
differential
lymphohistiocytosis
cytokines / metabolism
genetic predisposition to disease
cell proliferation
t-lymphocytes / metabolism
t-lymphocytes / immunology*
cellular*
pmid:17151879
doi:10.1007/s00431-006-0258-1
gritta e janka
hemophagocytic* / genetics
hemophagocytic* / immunology
hemophagocytic* / pathology
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116748
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