For the protection of human health, clean and safe drinking water supply is important. In connection with this, the drinking and irrigation water of village Darra Pezu and its neighboring areas of district Lakki Marwat, Pakistan was evaluated for different physical and chemical constraints including pH, electrical conductivity (EC), alkalinity, turbidity, hardness, total dissolved solids (TDS) and total suspended solids (TSS). The standard analytical procedures were adopted for the study of each of these parameter. The obtained results of each parameter were compared to the standard permissible limits given by the National Drinking Water Quality Standard (NDWQS) as well as World Health Organization (WHO) standards for drinking water and were found to be according to the safe limits prescribed by NDWQS and WHO except well water. The two well water samples of Wanda Sharbat and Wanda Gulmir have high pH, turbidity, EC, hardness, alkalinity, TDS, TSS values than that given by WHO and NDWQS. It is because the well water is open to atmosphere so due to which there is contamination by chemicals pollutants and high growth of algae. Overall, water from all the sources is reported irrigation while well water of the area is not fit for drinking and needs the government attention.