Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

Takeshi Imai, Reiko Takakuwa, Sandra Marchand, Emilie Dentz, Jean-Marc Bornert, Nadia Messaddeq, Olivia Wendling, Manuel Mark, Béatrice Desvergne, Walter Wahli, Pierre Chambon, Daniel Metzger;Takeshi Imai;Reiko Takakuwa;Sandra Marchand;Emilie Dentz;Jean-Marc Bornert;Nadia Messaddeq;Olivia Wendling;Manuel Mark;Béatrice Desvergne;Walter Wahli;Pierre Chambon;Daniel Metzger;
Proceedings of the National Academy of Sciences of the United States of America 2004 Vol. 101 pp. 4543-
144
metzger2004proceedingsperoxisome

Abstract

The peroxisome proliferator-activated receptor γ (PPARγ) mediates the activity of the insulin-sensitizing thiazolidinediones and plays an important role in adipocyte differentiation and fat accretion. The analysis of PPARγ functions ...

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