Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse
Takeshi Imai, Reiko Takakuwa, Sandra Marchand, Emilie Dentz, Jean-Marc Bornert, Nadia Messaddeq, Olivia Wendling, Manuel Mark, Béatrice Desvergne, Walter Wahli, Pierre Chambon, Daniel Metzger;Takeshi Imai;Reiko Takakuwa;Sandra Marchand;Emilie Dentz;Jean-Marc Bornert;Nadia Messaddeq;Olivia Wendling;Manuel Mark;Béatrice Desvergne;Walter Wahli;Pierre Chambon;Daniel Metzger;
Proceedings of the National Academy of Sciences of the United States of America2004Vol. 101pp. 4543-
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metzger2004proceedingsperoxisome
Abstract
The peroxisome proliferator-activated receptor γ (PPARγ) mediates the activity of the insulin-sensitizing thiazolidinediones and plays an important role in adipocyte differentiation and fat accretion. The analysis of PPARγ functions ...