Anthocyanins protect against ethanol-induced neuronal apoptosis via GABAB1 receptors intracellular signaling in prenatal rat hippocampal neurons
Abstract
Here, we investigated the possible involvement of gamma-aminobutyric acid B1 receptor (GABAB1R) in mediating the protective effects of black soybean anthocyanins against ethanol-induced apoptosis in prenatal hippocampal neurons because GABARs are known to play an important role in the development of …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
Rats
Sprague-Dawley
Hippocampus / pathology*
Receptors
neuroprotective agents / pharmacology*
apoptosis / drug effects*
signal transduction / drug effects*
neurons / drug effects
biomarkers / metabolism
nerve degeneration / pathology
neurons / pathology
calcium / metabolism
neurons / metabolism*
pmid:23645118
doi:10.1007/s12035-013-8458-y
shahid ali shah
ikram ullah
myeong ok kim
anthocyanins / pharmacology*
cell shape / drug effects
ethanol
fetus / drug effects
fetus / metabolism
hippocampus / embryology
homeostasis / drug effects
intracellular space / drug effects
intracellular space / metabolism
membrane potential
mitochondrial / drug effects
gaba-b / metabolism*
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116310
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