Levofloxacin cures experimental pneumonic plague in African green monkeys
Abstract
Levofloxacin cures established pneumonic plague when treatment is initiated after the onset of fever in the lethal aerosol-challenged AGM nonhuman primate model, and can be considered for treatment of other forms of plague. Levofloxacin may also be considered for primary presumptive-use, multi-agent …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
Disease Models
Animal
bacteremia / mortality
Survival Analysis
lung / pathology
anti-bacterial agents / administration & dosage*
radiography
levofloxacin*
chlorocebus aethiops
intravenous
infusions
bacteremia / drug therapy
pmid:21347450
pmc3035670
doi:10.1371/journal.pntd.0000959
robert colby layton
william mega
frederick koster
bacteremia / pathology
ofloxacin / administration & dosage*
plague / complications
plague / drug therapy*
plague / mortality
plague / pathology
primate diseases / drug therapy*
primate diseases / mortality
primate diseases / pathology
thoracic
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Citation
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116249
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