Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration
Abstract
Characterization of mitochondrial function and mitochondria-cytosol communications will provide pivotal opportunities for identifying targets and developing new strategies aimed at restoring the mitochondrial energy-redox axis that is compromised in brain aging and neurodegeneration.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
review
gene expression regulation
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
N.I.H.
Extramural
Cell Nucleus / genetics
transcription
signal transduction
neurodegenerative diseases / genetics
homeostasis
energy metabolism*
oxidation-reduction
brain / metabolism*
pmid:22793257
pmc3887431
doi:10.1089/ars.2012.4774
fei yin
alberto boveris
enrique cadenas
aging / metabolism*
cell nucleus / metabolism
cellular senescence
cytosol / metabolism
mitochondria / metabolism*
neurodegenerative diseases / metabolism*
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116186
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