Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear Translocation of Androgen Receptor Complex with β-Catenin and T-Cell Factor 4 May Bypass Canonical Wnt Signaling to Down-Regulate Adipogenic Transcription Factors

Testosterone Inhibits Adipogenic Differentiation in 3T3-L1 Cells: Nuclear Translocation of Androgen Receptor Complex with β-Catenin and T-Cell Factor 4 May Bypass Canonical Wnt Signaling to Down-Regulate Adipogenic Transcription Factors

Singh, Rajan;Artaza, Jorge N.;Taylor, Wayne E.;Braga, Melissa;Yuan, Xin;Gonzalez-Cadavid, Nestor F.;Bhasin, Shalender;
endocrinology 2006 Vol. 147 pp. 141-154
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rajan2006endocrinologytestosterone

Abstract

Testosterone supplementation in men decreases fat mass; however, the mechanisms by which it inhibits fat mass are unknown. We hypothesized that testosterone inh

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