Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
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Peptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.

D M Lambert, S Barney, A L Lambert, K Guthrie, R Medinas, D E Davis, T Bucy, J Erickson, G Merutka, S R Petteway, Jr;D M Lambert;S Barney;A L Lambert;K Guthrie;R Medinas;D E Davis;T Bucy;J Erickson;G Merutka;S R Petteway, Jr;
Proceedings of the National Academy of Sciences of the United States of America 1996 Vol. 93 pp. 2186-
92
jr1996proceedingspeptides

Abstract

The synthetic peptides DP-107 and DP-178 (T-20), derived from separate domains within the human immunodeficiency virus type 1 (HIV-1) transmembrane (TM) protein, gp4l, are stable and potent inhibitors of HIV-1 infection and fusion. Using a computer searching ...

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DOI:
10.1073/pnas.93.5.2186
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC39932/

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