Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study

Everolimus, Letrozole, and Metformin in Women with Advanced or Recurrent Endometrioid Endometrial Cancer: A Multi-Center, Single Arm, Phase II Study

Soliman PT;Westin SN;Iglesias DA;Fellman BM;Yuan Y;Zhang Q;Yates MS;Broaddus RR;Slomovitz BM;Lu KH;Coleman RL;;
clinical cancer research : an official journal of the american association for cancer research 2020 Vol. 26 pp. -
267
pt2020clinicaleverolimus,

Abstract

Everolimus, letrozole, and metformin resulted in 50% CB and 28% OR in women with recurrent EEC. Progesterone receptor-positive tumors may have better response; validation studies are needed.See related commentary by Madariaga et al., p. 523.

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