Metagenomic microbial community profiling using unique clade-specific marker genes
Abstract
Metagenomic shotgun sequencing data can identify microbes populating a microbial community and their proportions, but existing taxonomic profiling methods are inefficient for increasingly large data sets. We present an approach that uses clade-specific marker genes to unambiguously assign reads to m …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
reproducibility of results
research support
u.s. gov't
non-p.h.s.
N.I.H.
Extramural
Phylogeny*
bacteria / isolation & purification
bacteria / classification*
pmid:22688413
pmc3443552
doi:10.1038/nmeth.2066
nicola segata
levi waldron
curtis huttenhower
bacteria / genetics*
genetic markers / genetics*
metagenomics*
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115741
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