Prophylactic and preventive antibiotic therapy: timing, duration and economics
Abstract
Previous studies have demonstrated that administered antibiotics must be active against major anticipated pathogens and must have reached sufficient concentrations in the tissue or body fluid at risk by the time of bacterial challenge if prophylactic therapy is to be maximally effective in reducing …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
clinical trials as topic
humans
pubmed abstract
nih
national institutes of health
national library of medicine
female
male
middle aged
Drug Administration Schedule
Clinical Trial
Randomized Controlled Trial
Double-Blind Method
evaluation studies as topic
time factors
anti-bacterial agents / administration & dosage
anti-bacterial agents / therapeutic use*
costs and cost analysis
preoperative care
surgical wound infection / prevention & control*
pmid:378140
pmc1397224
doi:10.1097/00000658-197906000-00004
h h stone
b b haney
c a hooper
cefamandole / administration & dosage
cefamandole / therapeutic use
cephaloridine / administration & dosage
cephaloridine / therapeutic use
postoperative care / economics
surgical wound infection / economics
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Citation
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115697
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