In 8 cases, the following enzymes were studied in the dendritic swellings and torpedoes of Purkinje cells of cerebellum: succinic dehydrogenase, cytochrome oxidase, lactic dehydrogenase, NAD-diaphorase, alkaline phosphatase, acid phosphatase, acetyl cholinesterase and nonspecific cholinesterase. Activity of the oxidative enzymes was always extremely high in the dendritic swellings, but varied greatly among cases in the torpedoes; 4 cases showed very weak activity of oxidative enzymes in torpedoes, while 4 other cases showed an intense reaction. Dendritic swellings and torpedoes exhibited no alkaline phosphatase, acetyl cholinesterase, or nonspecific cholinesterase activity.