The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection
Abstract
We conclude that in surgical practice there is considerable variation in the timing of prophylactic administration of antibiotics and that administration in the two hours before surgery reduces the risk of wound infection.
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
adult
female
male
age factors
aged
middle aged
Prospective Studies
sex factors
P.H.S.
regression analysis
Clinical Trial
Randomized Controlled Trial
bacteria / drug effects
anti-bacterial agents / administration & dosage*
risk
bacteria / isolation & purification
surgical wound infection / microbiology
surgical wound infection / prevention & control*
pmid:1728731
doi:10.1056/nejm199201303260501
d c classen
r s evans
j p burke
premedication / methods*
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115485
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