Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: Clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant
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Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: Clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant

Ruth A. Karron, Deborah A. Buonagurio, Alice F. Georgiu, Stephen S. Whitehead, Jean E. Adamus, Mary Lou Clements-Mann, Denos O. Harris, Valerie B. Randolph, Stephen A. Udem, Brian R. Murphy, Mohinderjit S. Sidhu;Ruth A. Karron;Deborah A. Buonagurio;Alice F. Georgiu;Stephen S. Whitehead;Jean E. Adamus;Mary Lou Clements-Mann;Denos O. Harris;Valerie B. Randolph;Stephen A. Udem;Brian R. Murphy;Mohinderjit S. Sidhu;
Proceedings of the National Academy of Sciences of the United States of America 1997 Vol. 94 pp. 13961-
235
sidhu1997proceedingsrespiratory

Abstract

A live, cold-passaged (cp) candidate vaccine virus, designated respiratory syncytial virus (RSV) B1 cp-52/2B5 (cp-52), replicated efficiently in Vero cells, but was found to be overattenuated for RSV-seronegative infants and children. Sequence ...

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DOI:
10.1073/pnas.94.25.13961
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC28415/

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