Respiratory syncytical virus-induced chemokine expression in the lower airways: eosinophil recruitment and degranulation
Abstract
Characterization of chemokine expression patterns in virus-infected epithelial cells provides important clues to the pathophysiology of such infections. The aim of this study was to determine the chemokine response pattern of respiratory epithelium when infected with respiratory syncytial virus (RSV …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
respiratory syncytial virus infections / pathology
respiratory syncytial viruses / physiology
j b domachowske
eosinophil granule proteins
ribonucleases*
chemokines / metabolism*
eosinophil-derived neurotoxin
proteins / metabolism
pmid:10351940
doi:10.1164/ajrccm.159.6.9805083
a m harrison
c a bonville
blood proteins / biosynthesis
cell degranulation / physiology
cell line / virology
chemokine ccl4
chemokine ccl5 / metabolism
eosinophils / physiology
epithelial cells / metabolism
interleukin-8 / metabolism
macrophage inflammatory proteins / biosynthesis
peroxidase / metabolism
respiratory syncytial virus infections / metabolism*
respiratory system / metabolism*
respiratory system / pathology
virus activation / physiology
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114681
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