Usefulness of BCOR gene mutation as a prognostic factor in acute myeloid leukemia with intermediate cytogenetic prognosis
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Usefulness of BCOR gene mutation as a prognostic factor in acute myeloid leukemia with intermediate cytogenetic prognosis

Terada K;Yamaguchi H;Ueki T;Usuki K;Kobayashi Y;Tajika K;Gomi S;Kurosawa S;Saito R;Furuta Y;Miyadera K;Tokura T;Marumo A;Omori I;Sakaguchi M;Fujiwara Y;Yui S;Ryotokuji T;Arai K;Kitano T;Wakita S;Fukuda T;Inokuchi K;;
genes, chromosomes & cancer 2018 Vol. 57 pp. -
344
k2018genes,usefulness

Abstract

BCOR gene is a transcription regulatory factor that plays an essential role in normal hematopoiesis. The wider introduction of next-generation sequencing technology has led to reports in recent years of mutations in the BCOR gene in acute myeloid leukemia (AML), but the related clinical characterist …

Keywords

leukemia National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine prognosis female male aged middle aged hiroki yamaguchi survival rate koiti inokuchi myeloid acute / genetics* acute / pathology genetic predisposition to disease mutation* pmid:29663558 doi:10.1002/gcc.22542 kazuki terada cytogenetic analysis / methods high-throughput nucleotide sequencing acute / metabolism proto-oncogene proteins / genetics* repressor proteins / genetics* fms-like tyrosine kinase 3 / genetics

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