Adipose tissue insulin resistance in peripubertal girls with first-degree family history of polycystic ovary syndrome
Abstract
Girls at high risk of developing PCOS display increased adiposity and 17-OHP levels, but are mainly characterized by global insulin resistance and resistance to insulin-induced suppression of lipolysis that were independent of adiposity and 17-OHP levels. Therefore, genetic predisposition to PCOS ma …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
female
N.I.H.
Extramural
polycystic ovary syndrome / physiopathology*
adolescent
Child
Insulin Resistance*
pmid:22985947
pmc3902032
doi:10.1016/j.fertnstert.2012.08.025
andréanne trottier
marie-claude battista
jean-patrice baillargeon
adipose tissue / physiopathology*
metabolic syndrome / physiopathology*
puberty*
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113908
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