Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus
Graham BS;Henderson GS;Tang YW;Lu X;Neuzil KM;Colley DG;;
journal of immunology (baltimore, md : 1950)1993Vol. 151pp. -
374
bs1993journalpriming
Abstract
Defining the mechanism for the vaccine-enhanced illness associated with respiratory syncytial virus (RSV) is critical for advancing RSV vaccine development. Previous studies in which infants were vaccinated with formalin-inactivated alum-precipitated whole virus did not protect from RSV infection, a …