Metagenomic Analysis of Microdissected Valvular Tissue for Etiological Diagnosis of Blood Culture–Negative Endocarditis

Metagenomic Analysis of Microdissected Valvular Tissue for Etiological Diagnosis of Blood Culture–Negative Endocarditis

Million, Matthieu;Gaudin, Maxime;Melenotte, Cléa;Chasson, Lionel;Edouard, Sophie;Verdonk, Constance;Prudent, Elsa;Amphoux, Bernard;Meresse, Stéphane;Dorent, Richard;Lepidi, Hubert;La Scola, Bernard;Gorvel, Jean-Pierre;Desnues, Christelle;Raoult, Didier;
clinical infectious diseases 2020 Vol. 70 pp. 2405-2412
162
matthieu2020clinicalmetagenomic

Abstract

The diagnosis of infectious diseases by metagenomic shotgun sequencing is limited by background DNA. We show here, in a case of blood culture-negative endocardi

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