Maternal administration of melatonin prevents spatial learning and memory deficits induced by developmental ethanol and lead co-exposure
Abstract
Melatonin is a radical scavenger with the ability to remove reactive oxidant species. There is report that co-exposure to lead and ethanol during developmental stages induces learning and memory deficits and oxidative stress. Here, we studied the effect of melatonin, with strong antioxidant properti …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
pregnancy
research support
non-u.s. gov't
female
male
Ethanol / toxicity*
age factors
Drug Administration Schedule
newborn
Rats
analysis of variance
wistar
pmid:28209536
doi:10.1016/j.physbeh.2017.02.012
elham soleimani
iran goudarzi
taghi lashkarbolouki
antioxidants / administration & dosage*
catalase / metabolism
glutathione peroxidase / metabolism
hippocampus / drug effects
hippocampus / metabolism
lead / toxicity*
lipid peroxidation / drug effects
maternal exposure*
maze learning / drug effects
melatonin / administration & dosage*
memory disorders / chemically induced*
memory disorders / prevention & control*
spatial learning / drug effects
superoxide dismutase / metabolism
thiobarbituric acid reactive substances / metabolism
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113037
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