Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
Abstract
Peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) is an adipocyte-specific nuclear hormone receptor that has recently been identified as a key regulator of two fat cell enhancers. Transcriptional activation by PPAR gamma 2 is potentiated by a variety of lipids and lipid-like compound …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
gene expression regulation
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
cell line
3T3 Cells
CCAAT-Enhancer-Binding Proteins
Inbred BALB C
Receptors
Base Sequence
Molecular Sequence Data
mutation
adipocytes / cytology*
pmid:8001151
doi:10.1016/0092-8674(94)90006-x
p tontonoz
e hu
b m spiegelman
cell differentiation / physiology
dna-binding proteins / physiology
fatty acids / physiology
fibroblasts / cytology*
nuclear proteins / physiology
cytoplasmic and nuclear / biosynthesis
cytoplasmic and nuclear / physiology*
recombinant proteins / biosynthesis
transcription factors / biosynthesis
transcription factors / physiology*
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112048
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