Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling
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Abnormal Mitochondria in a Non-human Primate Model of MPTP-induced Parkinson's Disease: Drp1 and CDK5/p25 Signaling

Park J;Seo J;Won J;Yeo HG;Ahn YJ;Kim K;Jin YB;Koo BS;Lim KS;Jeong KJ;Kang P;Lee HY;Baek SH;Jeon CY;Hong JJ;Huh JW;Kim YH;Park SJ;Kim SU;Lee DS;Lee SR;Lee Y;;
experimental neurobiology 2019 Vol. 28 pp. -
165
j2019experimentalabnormal

Abstract

Mitochondria continuously fuse and divide to maintain homeostasis. An impairment in the balance between the fusion and fission processes can trigger mitochondrial dysfunction. Accumulating evidence suggests that mitochondrial dysfunction is related to neurodegenerative diseases such as Parkinson's d …

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National Center for Biotechnology Information NCBI NLM MEDLINE pubmed abstract nih national institutes of health national library of medicine pmid:31308800 pmc6614070 doi:10.5607/en.2019.28.3.414 junghyung park jincheol seo youngjeon lee

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