Impaired Humoral Response to Vaccines among HIV-Exposed Uninfected Infants
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Impaired Humoral Response to Vaccines among HIV-Exposed Uninfected Infants

Beatriz Mariana Abramczuk;Taís Nitsch Mazzola;Yara Maria Franco Moreno;Tatiane Queiroz Zorzeto;Wagner Quintilio;Paulo Silva Wolf;Maria Heloisa Blotta;André Moreno Morcillo;Marcos Tadeu Nolasco da Silva;Maria Marluce dos Santos Vilela;Beatriz Mariana Abramczuk;Taís Nitsch Mazzola;Yara Maria Franco Moreno;Tatiane Queiroz Zorzeto;Wagner Quintilio;Paulo Silva Wolf;Maria Heloisa Blotta;André Moreno Morcillo;Marcos Tadeu Nolasco da Silva;Maria Marluce dos Santos Vilela;
clinical and vaccine immunology 2011 Vol. 18 pp. 1406-1409
144
abramczuk2011clinicalimpaired

Abstract

Little is known about the vaccine protective response for infants born from HIV-infected mothers. We evaluated the antibody response to hepatitis B, tetanus, and diphtheria vaccine in vertically HIV-exposed uninfected infants and compared them to those of control infants not exposed to the virus. The quantitative determination of specific neutralizing antibodies against hepatitis B, diphtheria, and tetanus were performed blindly on serum samples. The results showed that 6.7% of the HIV-exposed uninfected individuals were nonresponders to hepatitis B vaccine (anti-HBs titer,

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DOI:
10.1128/CVI.05065-11
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https://doi.org/10.1128%2FCVI.05065-11

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